Dermatology, ENT, and Ophthalmology Medications

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Fluticasone (Flonase) is a nasal corticosteroid that is used in the management of allergic rhinitis.

A primary adverse effect that I have seen in practice with fluticasone is the risk for nose bleeds.

Flonase can have some interactions via CYP3A4. Inhibitors of CYP3A4 like clarithromycin can increase concentrations.

While the risk for systemic exposure is low with nasal fluticasone, long-term, high dose, and frequent use should be monitored appropriately.

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Latanoprost is a prostaglandin F2 analog that can help reduce intraocular pressure and manage glaucoma.

Excessive eyelash growth is a potential adverse effect of latanoprost, although some patients may appreciate this.

Patients with a lighter color iris may notice that their eyes are turning more brown with the chronic use of latanoprost.

Corticosteroids are known to increase intraocular pressure and potentially oppose the beneficial effects of latanoprost.

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