Caffeine Pharmacology

Caffeine is a commonly used supplement and is found in many food and beverages. I discuss caffeine pharmacology, adverse effects, and drug interactions.

Caffeine can inhibit CYP1A2 and also be affected by CYP1A2 inhibitors. I discuss some examples in the podcast.

It is critical to inquire about caffeine intake when patients are reporting insomnia.

Caffeine has been associated with increases in pulse and blood pressure. Be sure to ask about caffeine intake when assessing these vital signs.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Magnesium Pharmacology

Magnesium Pharmacology

On this episode, I discuss magnesium pharmacology and the clinical applications. Magnesium plays numerous important functions in the body and you may see patients take these supplements under the direction of a healthcare professional and sometimes on their own.

It is very important to remember that magnesium can cause GI upset and diarrhea. This is often overlooked in our polypharmacy patient.

Magnesium can accumulate in renal disease. This is important to remember especially in patients who have a tendency to take a lot of supplements without discussing them with a healthcare professional.

PPI’s are a notorious cause of low magnesium. Loop diuretics can increase magnesium excretion and also cause low magnesium levels.

Magnesium can bind up numerous drugs reducing concentrations and leading to treatment failure. A few examples include quinolone antibiotics, tetracycline antibiotics, and levothyroxine.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Iron Supplement Pharmacology

Iron supplements frequently cause GI upset. Monitor patients for nausea, vomiting, and constipation issues.

There are three main salt forms of iron. Ferrous fumurate has the most elemental iron, ferrous sulfate (2nd most), and ferrous gluconate has the least.

Iron can bind up antibiotics and reduce their effectiveness. Two classic examples include the quinolone and tetracycline antibiotics.

Anemia can be caused by numerous concerns, however, iron deficiency is a very common cause.

Ferritin is a lab that we commonly monitor in a patient who may be iron deficient. Iron deficiency can also lead to symptoms of Restless Leg Syndrome.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Potassium Supplement Pharmacology

On this episode I discuss why we may need to use potassium supplements.

I also talk about a medication error situation involving potassium that lead to a death.

It is important to remember other medications that can raise potassium levels.

I also talk about a dosage form of potassium that might make patients ask some questions.

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