Category: Endocrine Medications

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Thyroid Disorders – Section 4.5 – Free Nursing Pharmacology Review Course From Meded101

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This podcast episode gives nurses a practical, easy-to-apply overview of common thyroid disorders, focusing on how to recognize and manage both hypothyroidism and hyperthyroidism in clinical practice. It reviews key differences in presentation—such as fatigue, weight gain, and cold intolerance in hypothyroidism versus weight loss, tachycardia, and heat intolerance in hyperthyroidism—while connecting these symptoms to underlying physiology. Nurses will learn important medication considerations, including proper administration of levothyroxine and monitoring for adverse effects with methimazole. The episode also highlights critical safety topics like recognizing thyroid storm, interpreting lab values (TSH, T3, T4), and providing effective patient education. With real-world clinical pearls, this episode helps nurses build confidence in managing thyroid conditions across care settings.

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Insulin Therapy Section 4.4 – Free Nursing Pharmacology Review Course

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This podcast episode gives nurses a practical, bedside-focused guide to insulin therapy, helping simplify one of the most important—and often confusing—areas of diabetes management. It reviews key insulin types, including rapid-acting insulin lispro, long-acting insulin glargine, and intermediate options like NPH insulin, highlighting onset, peak, and duration differences that drive dosing decisions. Nurses will learn how to safely administer insulin, adjust for meals and blood glucose trends, and recognize and treat hypoglycemia quickly. Real-world clinical tips are included to help nurses feel confident managing insulin in both inpatient and outpatient settings.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Diabetes Medications Section 4.3 – Free Nursing Pharmacology Review Course

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This podcast episode provides nurses with a clear, practical overview of non-insulin diabetes medications, focusing on how to safely and effectively manage patients with type 2 diabetes. It reviews key drug classes such as metformin, glipizide, empagliflozin, and semaglutide, emphasizing mechanisms of action, common side effects, and important monitoring parameters. Nurses will learn how to recognize risks like hypoglycemia with sulfonylureas, genitourinary infections with SGLT2 inhibitors, and gastrointestinal effects with GLP-1 agents, along with key patient counseling points. The episode also connects medication selection to real-world considerations such as weight impact, cardiovascular benefit, and kidney function, helping nurses feel more confident in supporting individualized diabetes care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Diabetes Compelling Indications Section 4.2 – Free Nursing Pharmacology Review Course

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This podcast episode breaks down diabetes “compelling indications” in a way that’s highly practical for nurses managing complex patients. It explains how comorbid conditions like cardiovascular disease, heart failure, and chronic kidney disease influence medication selection beyond just lowering A1c.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Addison’s and Cushing’s Disease Section 4.1 – Nursing Pharmacology Review Course

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This podcast episode provides nurses with a practical, clinically focused overview of Addison’s disease and Cushing’s disease, highlighting key differences in pathophysiology, presentation, and management. Listeners will learn how adrenal insufficiency in Addison’s leads to symptoms like fatigue, hypotension, and hyperpigmentation, while excess cortisol in Cushing’s presents with weight gain, hypertension, and glucose intolerance. The episode emphasizes important nursing considerations such as recognizing adrenal crisis, monitoring electrolytes and blood pressure, patient education on steroid adherence, and identifying medication-related causes of Cushing’s.

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Fludrocortisone (Florinef) Pharmacology

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On this podcast episode, I cover fludrocortisone. Fludrocortisone is a synthetic corticosteroid with potent mineralocorticoid activity and minimal glucocorticoid effects. It works primarily by promoting sodium reabsorption and potassium excretion in the distal renal tubules, leading to increased water retention and expansion of extracellular fluid volume. This pharmacologic action helps maintain blood pressure and electrolyte balance.

Fludrocortisone is most commonly indicated for the treatment of adrenocortical insufficiency, such as Addison’s disease, and for managing orthostatic hypotension by enhancing vascular tone and volume status.

Adverse effects are typically related to its mineralocorticoid potency and may include hypertension, edema, hypokalemia, and weight gain. Long-term use can also lead to complications such as heart failure exacerbation, osteoporosis, and mood changes. Because of its sodium-retaining effects, careful monitoring of blood pressure, electrolytes, and signs of fluid overload is recommended during therapy.

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Linagliptin Pharmacology

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Today’s sponsor is Freed AI! Freed’s AI medical scribe listens, transcribes, and writes notes for you. Over 15,000 healthcare professionals use Freed and you should too! Learn more here!

On this episode of the Real Life Pharmacology Podcast, I cover linagliptin pharmacology, adverse effects, drug interactions, and much more.

Linagliptin is a DPP-4 inhibitor used to help control blood sugar levels in adults with type 2 diabetes. It works by increasing the levels of incretin hormones, which stimulate insulin release and decrease glucagon levels in the blood.

Linagliptin is usually taken once daily and can be used alone or in combination with other diabetes medications.

Unlike some other diabetes drugs, linagliptin does not usually cause weight gain or low blood sugar (hypoglycemia) when used alone.

Linagliptin should not be used with GLP-1 agonists as it works on a similar pathway as that medication class.

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Continuous Glucose Monitors Podcast

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Continuous Glucose Monitors (CGMs) are becoming an important tool in the management of diabetes. I break down some of the most common clinical practice pearls you should know.

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Beers Criteria Podcast Part 2 or 2

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On this podcast episode, I finish up my breakdown of the Beers Criteria.

I cover the use of sliding-scale insulin and sulfonylureas in geriatric patients. Hypoglycemia is a major concern with both of these diabetes management strategies.

PPIs show up on the Beers criteria list as they can increase the risk of C. diff, pneumonia, fractures, and GI malignancies.

Metoclopramide has dopamine antagonist activity and can increase the risk of EPS and tardive dyskinesia.

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Teplizumab For Diabetes Episode 315 – Real Life Pharmacology Podcast

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Teplizumab is a relatively new agent that helps delay the progression of type 1 diabetes. It slows the rate of beta-cell destruction in the pancreas.

Teplizumab is associated with cytokine release syndrome which can result in flu-like symptoms of fever, aches, and headache.

Cytokine release syndrome due to teplizumab can be reduced by using appropriate pretreatment medications. Those medications can include analgesics, antihistamines, and/or antiemetics.

Teplizumab is associated with suppressing the immune system so it is ideal to get vaccinations completed before using this medication. I go over the specific recommendations in the podcast episode.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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