Podcast

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On this episode, I talk about apixaban (Eliquis) pharmacology.

I also cover adverse effects like bleeding and what to monitor.

Drug interactions are a concern with apixaban and I discuss a few items that you may want to look out for.

It is important to remember that apixaban does require dose adjustments in certain situations as well.

Check out our free giveaway for healthcare professionals and students.  It is a top 200 study guide of highly testable pearls! (Free 31 page PDF)

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Metoclopramide Pharmacology

Metoclopramide can block dopamine receptors as part of it’s mechanism of action.  I discuss the clinical implications from this in the podcast.

Metoclopramide can exacerbate Parkison’s disorder so you need to be careful in that type of patient.

Metoclopramide is dosed frequently, which can potentially be a downside as far as patient adherence goes.

Metoclopramide has a few potential interactions that you should be aware of.  I talk about those in this episode.

Be sure to check out The Thrill of the Case on Amazon as I do have a clinical scenario about Reglan (metoclopramide) in that 200+ page book.

As always, check out my free Top 200 study guide!

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On this episode, I discuss the mechanism of action of the SGLT-2 Inhibitors and how they lower blood sugar.

These drugs are classically used for diabetes and eliminate blood sugar through the urine.

One of the potential side effects is that these drugs can increase the risk of genital infections and urinary tract infections.

There is a boxed warning on canagliflozin for its potential to increase the risk of amputation.

These drugs also have a mild diuretic type effect and can potentially cause hypotension.

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Cheers!

Eric Christianson, PharmD, BCGP, BCPS

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On this episode, I discuss how the tetracyclines impact bacterial protein synthesis.

I also remind you of several medications that fall in the tetracycline class.  Doxycycline is by far the medication I see used the most.

You’ll also learn about common side effects like GI upset and photosensitivity.

I cover why this class of medication is typically avoided in pediatrics and pregnancy.

I hope you enjoy the show and don’t forget to snag your FREE 31 page PDF study guide!

Podcast: Play in new window | Download (Duration: 8:13 — 11.8MB) | Embed

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I break down the mechanism of action, side effects, and important drug interactions you need to know. I give you a sense of what things you might actually encounter in practice when working with patients who take allopurinol.

Allopurinol is a top 200 drug. Remember to subscribe to the website reallifepharmacology.com for the Free 31 page PDF where I give you three highly testable pearls on the top 200 drugs.

In addition to the 31 page PDF for subscribing, you will get a free 100 question pharmacology test designed for healthcare professionals.

I hope you enjoy this episode the pharmacology of allopurinol!

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In this episode I discuss bupropion pharmacology.  I cover the mechanism of action, side effects, and some relevant drug interactions.

Important information in this episode includes:

• Possible indications for bupropion like depression and smoking cessation
• Risk of lowering seizure threshold
• Inhibition of CYP2D6
• Dosage form considerations
• Pearls for onset of bupropion’s action

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On this episode, I cover mirtazapine pharmacology.

We will review how mirtazapine works in the body and how those cause adverse effects and benefit out patient.

I will also look at the side effect profile and why mirtazapine may be harmful or helpful in our patients.

We cover drug interactions for mirtazapine in the podcast as well.

Mirtazapine is an antidepressant and I mention discontinuation syndrome as well as what I see as being done when converting a patient from one antidepressant to another.

Enjoy the show and don’t for get to get your free gift by subscribing!

Podcast: Play in new window | Download (Duration: 11:34 — 16.4MB) | Embed

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The Serotonin and Norepinephrine Reuptake Inhibitors are a class of medication used for various mental health disorder and pain syndromes.  I talk about the pharmacology of the SNRI’s and how it relates to their adverse effect profile.  The pharmacology of SNRI’s also plays an important role in why they are efficacious for treatment of pain compared to the SSRI’s.  In addition to the adverse effects, I will outline some common drug interactions and which medications might be affected by the SNRI’s. Enjoy the episode and I hope you pick up some clinical practice pearls with the SNRI’s!  Don’t forget to take advantage of our free giveaway as well, nearly 1,000 healthcare professionals and students have already done so!

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The TCA’s are one of the older antidepressant type medications that can be used for a whole host of reasons.  They are not without potential concerns however.  I cover the MOA, drug interactions, side effects and clinical practice pearls of the tricyclic antidepressants in this episode.

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Warfarin is one of the most notorious medications when it comes to drug interactions.  I cover the MOA, side effects, drug interactions, and pharmacology of the medication.  Enjoy the episode and don’t for get to subscribe to get our free study resources!