Infectious Disease Section 5.3- Antifungal Agents

Fungal infections are commonly encountered across healthcare settings, ranging from oral thrush and vaginal yeast infections to serious systemic infections in critically ill patients. In this episode, we’ll review the major antifungal medications nurses should know, including azoles, echinocandins, polyenes, and topical antifungals. We’ll focus on practical nursing considerations such as monitoring for adverse effects, recognizing important drug interactions, administration tips, and patient education points. By the end of the episode, listeners will have a stronger understanding of how antifungal medications work and how nurses play a key role in ensuring safe and effective treatment.

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Lotrisone (Clotrimazole/Betamethasone) Pharmacology

Lotrisone is a topical cream that contains a combination of clotrimazole, an antifungal, and betamethasone dipropionate, a corticosteroid.

It is used to treat fungal skin infections such as athlete’s foot, jock itch, and ringworm that also involve inflammation or itching.

Clotrimazole works by disrupting the fungal cell membrane, while betamethasone reduces redness, swelling, and itching.

Lotrisone should not be used on the face, groin, or underarms for extended periods due to the risk of skin thinning and other steroid-related side effects.

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