Opioids Part 4 – Methadone and Buprenorphine

In this episode of Real Life Pharmacology, we’re taking a closer look at two unique opioids: methadone and buprenorphine. Both medications have important roles in pain management and opioid use disorder, but their pharmacology, dosing, drug interactions, and safety considerations are quite different. We’ll review the key clinical pearls you need to know when using these medications in real-world practice.

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Buprenorphine/Naloxone Pharmacology Podcast

On this episode, I discuss the use of buprenorphine/naloxone in managing opioid use disorder. I cover the kinetics, dosage forms, adverse effect, interactions and much more.

Buprenorphine/naloxone has numerous dosage form and they are not interchangeable. I discuss this further on the podcast.

Liver impairment is a potential reason to avoid the use of buprenorphine. I discuss this on the podcast.

You must keep an eye out for withdrawal symptoms when initiating and adjusting doses of buprenorphine/naloxone. They include sweating, nausea, tachycardia, and mood changes.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

Support The Podcast and Check Out These Amazing Resources!

NAPLEX Study Materials

BCPS Study Materials

BCACP Study Materials

BCGP Study Materials

BCMTMS Study Materials

Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Pharmacy Technician Study Guide by Meded101