A Meded101.com Production
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On this podcast episode, we will explore the most important practice pearls of codeine and fentanyl. Both medications are opioids, but codeine is frequently found in combination with acetaminophen. Fentanyl has numerous unique dosage forms, including the transdermal formulation which is a source of frequent test questions. I break these two medications down in this podcast episode.
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On this episode, I discuss codeine pharmacology and practical clinical practice pearls.
Codeine is metabolized by CYP2D6 to the active metabolite morphine. I discuss how this can be affected by genetics as well as other medications.
Constipation is a problem with codeine and all opioids in general. Education and making a plan with patients to combat this side effect is important.
Codeine is less potent than other opioids such as fentanyl, hydromorphone, and hydrocodone.
I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.
Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!