Tag: naproxen

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NSAIDs Part 2 – Test Prep and Practice Pearls for Aspirin, Ibuprofen, Naproxen, and Celecoxib

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Aspirin, ibuprofen, naproxen, and celecoxib are some of the most commonly used NSAIDs, but they are not interchangeable when it comes to safety, indications, and patient-specific risks. In this episode of Real Life Pharmacology, we compare these four medications and highlight the key differences pharmacists and other healthcare professionals need to know.

We’ll review how NSAIDs work, including COX-1 and COX-2 inhibition, and discuss their effects on pain, inflammation, platelets, the gastrointestinal system, kidneys, cardiovascular system, and fluid balance. We’ll also compare the GI, cardiovascular, renal, and heart failure risks of aspirin, ibuprofen, naproxen, and celecoxib.

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Top 200 Drugs Podcast – Medications 91-95

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On this episode of the Real Life Pharmacology Podcast, I cover 5 more medications of the top 200.

Fenofibrate is a medication used primarily to reduce triglycerides. This medication differs from statins which tend to focus on LDL management.

Doxazosin is an alpha-blocker. The primary indications of doxazosin are hypertension and BPH.

Naproxen is an NSAID. Of all the NSAIDs, naproxen is one of the lower-risk agents with regard to cardiovascular risk.

Spironolactone is an aldosterone antagonist and also classified as a potassium sparing diuretic.

Memantine is an NMDA antagonist that is indicated for the management of Alzheimer’s dementia.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Naproxen Pharmacology

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On this episode of the Real Life Pharmacology Podcast, I discuss naproxen pharmacology.

Naproxen can raise the concentrations of lithium and increase the risk for toxicity.

Compared to most other NSAIDs, naproxen tends to have a lower cardiovascular risk.

Naproxen can contribute to renal insufficiency, GI bleed risk, and CHF exacerbations.

I discuss important drug interactions on the podcast, be sure to check out my latest project which is a 200+ page book on managing drug interactions in primary care.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!