Top 200 Drugs Podcast – Drugs 36-40

On this episode of the Real Life Pharmacology podcast, I continue my coverage with the Top 200 Drugs Podcast. Here’s the list of medications we will cover.

  • Lorazepam (Ativan) is a benzodiazepine well known for its anxiolytic and anti-seizure properties.
  • Phenazopyridine (Pyridium) is a urinary analgesic that can change the color of the urine to a reddish/orange color as one of its adverse effects.
  • Hydroxychloroquine (Plaquenil) is a DMARD used in rheumatoid arthritis and Lupus. One highly testable and unique nugget to remember is that it can cause retinopathy.
  • Lidocaine patch (Lidoderm) is used topically to help with various types of pain including neuropathy and postherpetic neuralgia.
  • Diclofenac (Cataflam) is an NSAID used as an analgesic and anti-inflammatory. It can increase the risk of GI bleed, edema, renal failure, and thrombosis.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Top 200 Drugs Podcast – Drugs 31-35

On this episode of the Real Life Pharmacology podcast, I discuss drugs 31-35 of the top 200 drugs.

Ethinyl estradiol/drospirenone is a combined oral contraceptive used for birth control purposes.

Hydralazine is a direct vasodilatory that can be used for hypertension and heart failure.

Benztropine is an older anticholinergic medication originally indicated for Parkinson’s disease but most commonly used to manage EPS symptoms from dopamine-blocking agents such as antipsychotics.

Tussionex is a combination medication of chlorpheniramine and hydrocodone. It is used to help alleviate cough.

Paroxetine is an SSRI used for the treatment of depression, anxiety, and other psychiatric disorders.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Top 200 Drugs Pharmacology Podcast – Drugs 26-30

On this episode of the Top 200 Drugs pharmacology podcast, I cover fluticasone nasal spray, allopurinol, alendronate, famotidine, and cefdinir.

Fluticasone is a corticosteroid that can be used nasally for the treatment of allergic rhinitis.

Allopurinol is a xanthine oxidase inhibitor used to reduce uric acid and prevent gout flares.

Alendronate is a bisphosphonate that inhibits the action of osteoclasts. This action helps treat osteoporosis.

Famotidine is a histamine-2 receptor antagonist that helps reduce gastric acid secretion and alleviate heartburn symptoms.

Cefdinir is a third-generation cephalosporin that is often used as an alternative for those who cannot take penicillin antibiotics. There is a small risk for cross-reactivity that a clinician has to consider.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Top 200 Drugs Podcast – Drugs 21-25

Lamotrigine is an antiseizure medication and also may be used for bipolar disorder. A rash is a major side effect to remember with this medication.

Valganciclovir is an antiviral medication that can be used to prevent cytomegalovirus (CMV) in patients with a suppressed immune system.

Fluconazole is an azole antifungal that can be used to treat candidiasis, blastomycosis, and tinea infections. Drug interactions, QTc prolongation, and hepatotoxicity are potential risks.

Atenolol is a beta-blocker used to treat atrial fibrillation and hypertension. It is relatively selective for beta-1 receptors meaning that it doesn’t affect the lungs as much as non-selective agents.

Montelukast is a medication that blocks the actions of leukotrienes. This can be beneficial for the management of allergies and asthma.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Top 200 Drugs Pharmacology Podcast – Drugs 11-15

Metformin is a medication used in the management of diabetes. It can cause significant diarrhea, B12 deficiency, and in rare cases, lactic acidosis.

Atorvastatin (Lipitor) is a statin medication used for cholesterol management. It lowers LDL and is associated with myopathy.

Omeprazole is a PPI used for GERD and has drug interactions with citalopram and clopidogrel.

Ciprofloxacin is a quinolone antibiotic used to treat gram-negative infections and UTIs. It carries numerous risks such as tendon rupture.

Ondansetron is an antiemetic medication used in the management of nausea and vomiting. I discuss the prescribing cascade in relation to this medication.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Timolol Pharmacology Podcast

On this episode, I discuss timolol pharmacology, adverse effects, drug interactions, and much more.

Timolol is a non-selective beta-blocker so it blocks both beta-1 and beta-2 receptors.

Since timolol blocks beta-2 receptors, it can blunt the effect of respiratory medications that have beta-agonist action.

Beta-blockers are notorious for causing bradycardia and pulse is an important monitoring parameter for timolol.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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10 Commandments of Polypharmacy Part 2 of 2

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Here is part 2 of 2 on the final 5 of the 10 commandments of polypharmacy.

6. Thou shalt identify limits for medications not intended for chronic use as well as not continue a medication indefinitely for symptoms that have an expected short duration

7. Thou shalt not start a medication from a similar medication class without appropriate rationale

8. Thou shalt not initiate a medication without considering medications that may treat duplicate conditions – Kill two birds with one stone

9. Thou shalt consider eliminating or reducing medications at every medication review

10. Thou shalt be willing to accept risk in discontinuing a medication if they were willing to accept the risk of initiating a medication

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Beers Criteria Podcast Part 2 or 2

On this podcast episode, I finish up my breakdown of the Beers Criteria.

I cover the use of sliding-scale insulin and sulfonylureas in geriatric patients. Hypoglycemia is a major concern with both of these diabetes management strategies.

PPIs show up on the Beers criteria list as they can increase the risk of C. diff, pneumonia, fractures, and GI malignancies.

Metoclopramide has dopamine antagonist activity and can increase the risk of EPS and tardive dyskinesia.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Beers Criteria Podcast Part 1 or 2

In this podcast episode, I break down some of the most common medications that show up on the Beers criteria list.

I discuss cardiovascular medications in this podcast episode, including rivaroxaban and warfarin, and why they show up on the Beers list.

Alpha-blockers who up on the Beers list as these medications are inappropriate to use for the management of hypertension.

The Beers criteria addresses the use of aspirin in primary prevention. I break down what the criteria state and why it should be avoided in general.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Navigating QTc Prolongation and Drug Interactions

On this episode, I discuss the pharmacology surrounding QTc prolongation and drug interactions.

I discuss which medications are more likely to cause QTc prolongation and which patient populations we should be more concerned about.

Antiarrhythmics are a common class of medication that can exacerbate QTc prolongation when used with other interacting medications.

500 ms is a common value utilized to help identify patients at risk for QTc prolongation and ultimately torsades de pointes.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)