SGLT-2 Inhibitors Pharmacology

On this episode, I discuss the mechanism of action of the SGLT-2 Inhibitors and how they lower blood sugar.

These drugs are classically used for diabetes and eliminate blood sugar through the urine.

One of the potential side effects is that these drugs can increase the risk of genital infections and urinary tract infections.

There is a boxed warning on canagliflozin for its potential to increase the risk of amputation.

These drugs also have a mild diuretic type effect and can potentially cause hypotension.

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Cheers!

Eric Christianson, PharmD, BCGP, BCPS

Tetracyclines Pharmacology Episode 038

On this episode, I discuss how the tetracyclines impact bacterial protein synthesis.

I also remind you of several medications that fall in the tetracycline class.  Doxycycline is by far the medication I see used the most.

You’ll also learn about common side effects like GI upset and photosensitivity.

I cover why this class of medication is typically avoided in pediatrics and pregnancy.

I hope you enjoy the show and don’t forget to snag your FREE 31 page PDF study guide!

Allopurinol Pharmacology

I break down the mechanism of action, side effects, and important drug interactions you need to know. I give you a sense of what things you might actually encounter in practice when working with patients who take allopurinol.

Allopurinol is a top 200 drug. Remember to subscribe to the website reallifepharmacology.com for the Free 31 page PDF where I give you three highly testable pearls on the top 200 drugs.

In addition to the 31 page PDF for subscribing, you will get a free 100 question pharmacology test designed for healthcare professionals.

I hope you enjoy this episode the pharmacology of allopurinol!

Bupropion Pharmacology – Real Life Pharmacology

In this episode I discuss bupropion pharmacology.  I cover the mechanism of action, side effects, and some relevant drug interactions.

Important information in this episode includes:

  • Possible indications for bupropion like depression and smoking cessation
  • Risk of lowering seizure threshold
  • Inhibition of CYP2D6
  • Dosage form considerations
  • Pearls for onset of bupropion’s action

Mirtazapine Pharmacology

On this episode, I cover mirtazapine pharmacology.

We will review how mirtazapine works in the body and how those cause adverse effects and benefit out patient.

I will also look at the side effect profile and why mirtazapine may be harmful or helpful in our patients.

We cover drug interactions for mirtazapine in the podcast as well.

Mirtazapine is an antidepressant and I mention discontinuation syndrome as well as what I see as being done when converting a patient from one antidepressant to another.

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Serotonin and Norepinephrine Reuptake Inhibitors Pharmacology

The Serotonin and Norepinephrine Reuptake Inhibitors are a class of medication used for various mental health disorder and pain syndromes.  I talk about the pharmacology of the SNRI’s and how it relates to their adverse effect profile.  The pharmacology of SNRI’s also plays an important role in why they are efficacious for treatment of pain compared to the SSRI’s.  In addition to the adverse effects, I will outline some common drug interactions and which medications might be affected by the SNRI’s. Enjoy the episode and I hope you pick up some clinical practice pearls with the SNRI’s!  Don’t forget to take advantage of our free giveaway as well, nearly 1,000 healthcare professionals and students have already done so!

Tricyclic Antidepressant Pharmacology

The TCA’s are one of the older antidepressant type medications that can be used for a whole host of reasons.  They are not without potential concerns however.  I cover the MOA, drug interactions, side effects and clinical practice pearls of the tricyclic antidepressants in this episode.

Carbidopa/Levodopa Pharmacology RLP Episode 031

On today’s episode, I talk about the pharmacology of carbidopa/levodopa.  We cover drug interactions, adverse effects, mechanism of action and why is this drug dose so frequently? Hope you enjoy the show and take advantage of our FREE giveaway, simply for following the show!

Aldosterone Antagonist Pharmacology RLP Episode 030

On today’s episode, I discuss spironolactone and eplerenone.  We cover the mechanism of action, monitoring parameters, adverse effects, and of course notable drug interactions.  Enjoy the show and please take advantage of our FREE giveaway by following the podcast via email!