Meperidine Pharmacology Podcast

On this podcast episode, I discuss meperidine pharmacology, adverse effects, pharmacokinetics, drug interactions, and much more!

Meperidine is an opioid that is seldom used due to neurotoxicity. I describe how this can happen in this podcast episode.

Meperidine has numerous drug interactions and using a CYP3A4 inhibitor may increase the risk for toxicity.

Seizures are a risk with meperidine due to its neurotoxic metabolite normeperidine. I discuss this further in this podcast episode.

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Guanfacine Pharmacology Podcast

On this episode of the podcast, I cover guanfacine pharmacology, adverse effects, drug interactions, and much more.

Guanfacine is a central acting alpha-2 agonist that has the brand names of Tenex and Intuniv.

Because of guanfacine’s mechanism of action, it suppresses the sympathetic response leading to a drop in pulse and blood pressure.

It is important to remind patients that the onset of action is slow in the management of ADHD with guanfacine. I discuss this further in this podcast episode.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Fluvastatin Pharmacolgy Podcast

On this podcast episode, I discuss fluvastatin pharmacology, adverse effects, pharmacokinetics, and much more.

Fluvastatin is only a low to moderate-intensity statin which explains its limited use compared to rosuvastatin or atorvastatin.

I discuss drug interactions in the podcast but one important one to recognize is drugs that can inhibit CYP2C9.

Fluvastatin is considered a lipophilic statin. I have previously discussed this on the Meded101 blog which you can find here.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Oxymorphone Pharmacology Podcast

In this episode, I discuss oxymorphone pharmacology, adverse effects, drug interactions, and more!

Oxymorphone is approximately 3 times more potent than morphine. I break down some common opioid comparisons in this episode.

Oxymorphone avoids many of the CYP interactions. I discuss some of the common interactions in this episode.

I discuss histamine release in relation to opioids and oxymorphone and specifically how this may impact our patients.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Diclofenac Pharmacology Podcast

On this podcast episode, I discuss diclofenac pharmacology, adverse effects, drug interactions, and much more.

Diclofenac is one of the highest-risk NSAIDs when it comes to cardiovascular risk. You can find more information on this in the Meded101 NSAID comparison table.

Diclofenac carries two boxed warnings. One is for GI bleed risk and the other is for cardiovascular risks.

Anticoagulants, antiplatelets, diuretics, and ACEs/ARBs are all common medication classes that can interact with diclofenac.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Aliskiren Pharmacology Podcast

On this episode, I discuss aliskiren pharmacology, adverse effects, drug interactions, and much more.

Aliskiren should not be used with ACE Inhibitors or ARBs. I discuss why that is in this episode.

Aliskiren has a long enough half-life at approximately 24 hours so it is recommended to only take this once daily.

Hyperkalemia is a major concern with aliskiren. It is important to monitor potassium levels and renal function.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

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Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Buprenorphine/Naloxone Pharmacology Podcast

On this episode, I discuss the use of buprenorphine/naloxone in managing opioid use disorder. I cover the kinetics, dosage forms, adverse effect, interactions and much more.

Buprenorphine/naloxone has numerous dosage form and they are not interchangeable. I discuss this further on the podcast.

Liver impairment is a potential reason to avoid the use of buprenorphine. I discuss this on the podcast.

You must keep an eye out for withdrawal symptoms when initiating and adjusting doses of buprenorphine/naloxone. They include sweating, nausea, tachycardia, and mood changes.

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Spironolactone Pharmacology Podcast

On this episode, I discuss spironolactone pharmacology, adverse effects, drug interactions and much more.

Spironolactone has numerous indications including hypertension, CHF, ascites, and acne. I break them all down in this podcast episode.

Hyperkalemia is a major concern with spironolactone. Patients with baseline levels at 5 or above should generally avoid this medication.

Gynecomastia is one of the most commonly tested adverse effects of spironolactone. Be sure you don’t miss this one on your board and pharmacology exams!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Meloxicam Pharmacology Podcast

I discuss meloxicam pharmacology, adverse effects, drug interactions, and much more on this episode of the Real Life Pharmacology Podcast.

Meloxicam tends to have a greater affinity to COX-2 versus COX-1. I discuss what this means clinically on this episode.

Important meloxicam drug interactions include anticoagulants, antiplatelet medications, renal impairing drugs, and lithium amongst others.

Meloxicam has a longer half-life than many NSAIDs and because of this can be dosed once daily for pain relief.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)

Enalapril Pharmacology Podcast

On this episode, I discuss enalapril pharmacology, adverse effects, drug interactions, and much more!

Enalapril has a shorter half-life compared to some of the other ACE inhibitors so it may need to be dosed twice daily in patients with adequate renal function.

Hyperkalemia, cough, renal impairment, and angioedema and four adverse effects associated with enalapril that you should monitor for.

NSAIDs and diuretics can increase the risk of acute renal failure when an ACE inhibitor like enalapril is being used.

Be sure to check out our free Top 200 study guide – a 31 page PDF that is yours for FREE!

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Flippin’ Pharmacology Flash Cards

Pharmacology Crossword Puzzle Book (Over 2,000 Clues/Questions!)

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Meded101 Guide to Nursing Pharmacology (Amazon Highly Rated)

Guide to Drug Food Interactions (Amazon Best Seller)

Drug Interactions In Primary Care (Amazing Resource for Practicing Clinicians)

Perils of Polypharmacy (Great Resource for Those Who Work in Geriatrics)