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On this podcast episode, I discuss tamoxifen pharmacology, adverse effects, drug interaction, and much more.
Tamoxifen is converted to a more active compound in the body by CYP2D6.
CYP2D6 inhibitors such as paroxetine, fluoxetine, or bupropion can essentially reduce the effectiveness of tamoxifen.
Hot flashes are a common adverse effect of tamoxifen and I discuss a few pharmacologic options to manage this adverse effect.
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